Multiple Cerebral Microbleeds: MRI Marker of a Diffuse Hemorrhage-Prone State

Julio A. Chalela; Dong Wha Kang; Steven Warach

doi:10.1177/1051228403258673

Multiple Cerebral Microbleeds: MRI Marker of a Diffuse Hemorrhage-Prone State

Julio A. Chalela, Dong Wha Kang, Steven Warach

Neurology & Neurotherapeutics

Research output: Contribution to journal › Article › peer-review

59 Scopus citations

Abstract

Background. Recent reports have indicated that cerebral microbleeds (CMBs) detected on gradient-echo (GRE) magnetic resonance imaging may be a risk factor for therapy-related intracranial hemorrhages (ICHs). Case Description. The authors describe 3 patients with multiple CMBs in whom ICHs occurred either after tissue plasminogen activator administration or after the initiation of antiplatelet therapy. Hemorrhages occurred in brain areas with normal appearances on GRE imaging and remote from the CMBs. Conclusion. Multiple CMBs may signal a diffuse hemorrhage-prone vasculopathy.

Original language	English (US)
Pages (from-to)	54-57
Number of pages	4
Journal	Journal of Neuroimaging
Volume	14
Issue number	1
DOIs	https://doi.org/10.1177/1051228403258673
State	Published - Jan 2004

Keywords

Gradient-echo imaging
Hemorrhage risk
Microbleeds

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Clinical Neurology

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10.1177/1051228403258673

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abstract = "Background. Recent reports have indicated that cerebral microbleeds (CMBs) detected on gradient-echo (GRE) magnetic resonance imaging may be a risk factor for therapy-related intracranial hemorrhages (ICHs). Case Description. The authors describe 3 patients with multiple CMBs in whom ICHs occurred either after tissue plasminogen activator administration or after the initiation of antiplatelet therapy. Hemorrhages occurred in brain areas with normal appearances on GRE imaging and remote from the CMBs. Conclusion. Multiple CMBs may signal a diffuse hemorrhage-prone vasculopathy.",

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N2 - Background. Recent reports have indicated that cerebral microbleeds (CMBs) detected on gradient-echo (GRE) magnetic resonance imaging may be a risk factor for therapy-related intracranial hemorrhages (ICHs). Case Description. The authors describe 3 patients with multiple CMBs in whom ICHs occurred either after tissue plasminogen activator administration or after the initiation of antiplatelet therapy. Hemorrhages occurred in brain areas with normal appearances on GRE imaging and remote from the CMBs. Conclusion. Multiple CMBs may signal a diffuse hemorrhage-prone vasculopathy.

AB - Background. Recent reports have indicated that cerebral microbleeds (CMBs) detected on gradient-echo (GRE) magnetic resonance imaging may be a risk factor for therapy-related intracranial hemorrhages (ICHs). Case Description. The authors describe 3 patients with multiple CMBs in whom ICHs occurred either after tissue plasminogen activator administration or after the initiation of antiplatelet therapy. Hemorrhages occurred in brain areas with normal appearances on GRE imaging and remote from the CMBs. Conclusion. Multiple CMBs may signal a diffuse hemorrhage-prone vasculopathy.

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Multiple Cerebral Microbleeds: MRI Marker of a Diffuse Hemorrhage-Prone State

Abstract

Keywords

ASJC Scopus subject areas

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