Multimodality Management of Trigeminal Schwannomas

Ajay Niranjan, Samuel Barnett, Vijay Anand, Siviero Agazzi

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Patients presenting with trigeminal schwannomas require multimodality management by a skull base surgical team that can offer expertise in both transcranial and transnasal approaches as well as radiosurgical and microsurgical strategies. Improvement in neurologic symptoms, preservation of cranial nerve function, and control of mass effect are the primary goals of management for trigeminal schwannomas. Complete surgical resection is the treatment of choice but may not be possible in all cases. Radiosurgery is an option as primary management for small- to moderate-sized tumors and can be used for postoperative residuals or recurrences. Planned surgical resection followed by SRS for residual tumor is an effective option for larger trigeminal schwannomas. The endoscopic resection is an excellent approach for patients with an extradural tumor or tumors isolated to the Meckel cave. A detailed analysis of a tumor and its surroundings based on high-quality imaging can help better estimate the expected outcome from each treatment. An expert skull base team should be able to provide precise counseling for each patient's situation for selecting the best option.

Original languageEnglish (US)
Pages (from-to)371-378
Number of pages8
JournalJournal of Neurological Surgery, Part B: Skull Base
Issue number4
StatePublished - Aug 1 2016


  • endoscopic resection
  • radiosurgery
  • skull base
  • transnasal approaches
  • trigeminal schwannomas

ASJC Scopus subject areas

  • Clinical Neurology


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