Multi-frequency PARACEST agents based on europium(III)DOTA-tetraamide ligands

Subha Viswanathan; S. James Ratnakar; Kayla N. Green; Zoltan Kovacs; Luis M. De Leónrodríguez; A. Dean Sherry

doi:10.1002/anie.200904649

Multi-frequency PARACEST agents based on europium(III)DOTA-tetraamide ligands

Subha Viswanathan, S. James Ratnakar, Kayla N. Green, Zoltan Kovacs, Luis M. De Leónrodríguez, A. Dean Sherry

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

Chemical Equation Presentation Colorful palette: A new class of highly selective Eu³⁺-based multi-frequency PARACEST agents is reported. The complexes can be tuned when administered simultaneously thereby allowing for the possibility of monitoring multiple biomarkers in parallel. PARACEST = paramagnetic chemical exchange saturation transfer.

Original language	English (US)
Pages (from-to)	9330-9333
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	48
Issue number	49
DOIs	https://doi.org/10.1002/anie.200904649
State	Published - Nov 23 2009

Keywords

Europium
Imaging agents
Macrocycles
PARACEST
Saturation transfer

ASJC Scopus subject areas

Catalysis
Chemistry(all)

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10.1002/anie.200904649

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title = "Multi-frequency PARACEST agents based on europium(III)DOTA-tetraamide ligands",

abstract = "Chemical Equation Presentation Colorful palette: A new class of highly selective Eu3+-based multi-frequency PARACEST agents is reported. The complexes can be tuned when administered simultaneously thereby allowing for the possibility of monitoring multiple biomarkers in parallel. PARACEST = paramagnetic chemical exchange saturation transfer.",

keywords = "Europium, Imaging agents, Macrocycles, PARACEST, Saturation transfer",

author = "Subha Viswanathan and Ratnakar, {S. James} and Green, {Kayla N.} and Zoltan Kovacs and {De Le{\'o}nrodr{\'i}guez}, {Luis M.} and {Dean Sherry}, A.",

year = "2009",

month = nov,

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language = "English (US)",

volume = "48",

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T1 - Multi-frequency PARACEST agents based on europium(III)DOTA-tetraamide ligands

AU - Viswanathan, Subha

AU - Ratnakar, S. James

AU - Green, Kayla N.

AU - Kovacs, Zoltan

AU - De Leónrodríguez, Luis M.

AU - Dean Sherry, A.

PY - 2009/11/23

Y1 - 2009/11/23

N2 - Chemical Equation Presentation Colorful palette: A new class of highly selective Eu3+-based multi-frequency PARACEST agents is reported. The complexes can be tuned when administered simultaneously thereby allowing for the possibility of monitoring multiple biomarkers in parallel. PARACEST = paramagnetic chemical exchange saturation transfer.

AB - Chemical Equation Presentation Colorful palette: A new class of highly selective Eu3+-based multi-frequency PARACEST agents is reported. The complexes can be tuned when administered simultaneously thereby allowing for the possibility of monitoring multiple biomarkers in parallel. PARACEST = paramagnetic chemical exchange saturation transfer.

KW - Europium

KW - Imaging agents

KW - Macrocycles

KW - PARACEST

KW - Saturation transfer

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U2 - 10.1002/anie.200904649

DO - 10.1002/anie.200904649

M3 - Article

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JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 49

ER -

Multi-frequency PARACEST agents based on europium(III)DOTA-tetraamide ligands

Abstract

Keywords

ASJC Scopus subject areas

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