Mucinous cystadenocarcinoma of the testis: A case report

Alina Cornelia Iuga; Jason Mull; Rashmi Batra; William Miller

doi:10.1016/j.humpath.2010.11.021

Mucinous cystadenocarcinoma of the testis: A case report

Alina Cornelia Iuga, Jason Mull, Rashmi Batra, William Miller

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

We present a rare case of unilateral intratesticular cystadenocarcinoma with mucinous differentiation in a 71-year-old male patient. The orchiectomy specimen revealed a 3.5-cm well to moderately differentiated cystic neoplasm with elongated fine papillary structures lined by columnar epithelium with alternating goblet and ciliated cells completely replacing the testicular parenchyma. Immunohistochemical studies showed positivity for cytokeratin 20, carcinoembryonic antigen, and mucin 2, and negativity for cytokeratin 7, mucin 5AC, vimentin, thyroid transcription factor 1, Wilms' tumor 1, and cancer antigen 125. The current case shows a focal cyst-lining component with benign appearance. Imaging studies and colonoscopy showed no evidence of other suspicious lesions. This tumor resembles morphologically to an intestinal-type ovarian surface epithelial tumor.

Original language	English (US)
Pages (from-to)	1343-1347
Number of pages	5
Journal	Human Pathology
Volume	42
Issue number	9
DOIs	https://doi.org/10.1016/j.humpath.2010.11.021
State	Published - Sep 2011

Keywords

Cyst
Cystadenocarcinoma
Intestinal
Intratesticular
Mucinous
Ovarian surface epithelial tumor
Testicular adenocarcinoma
Testis

ASJC Scopus subject areas

Pathology and Forensic Medicine

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10.1016/j.humpath.2010.11.021

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title = "Mucinous cystadenocarcinoma of the testis: A case report",

abstract = "We present a rare case of unilateral intratesticular cystadenocarcinoma with mucinous differentiation in a 71-year-old male patient. The orchiectomy specimen revealed a 3.5-cm well to moderately differentiated cystic neoplasm with elongated fine papillary structures lined by columnar epithelium with alternating goblet and ciliated cells completely replacing the testicular parenchyma. Immunohistochemical studies showed positivity for cytokeratin 20, carcinoembryonic antigen, and mucin 2, and negativity for cytokeratin 7, mucin 5AC, vimentin, thyroid transcription factor 1, Wilms' tumor 1, and cancer antigen 125. The current case shows a focal cyst-lining component with benign appearance. Imaging studies and colonoscopy showed no evidence of other suspicious lesions. This tumor resembles morphologically to an intestinal-type ovarian surface epithelial tumor.",

keywords = "Cyst, Cystadenocarcinoma, Intestinal, Intratesticular, Mucinous, Ovarian surface epithelial tumor, Testicular adenocarcinoma, Testis",

author = "Iuga, {Alina Cornelia} and Jason Mull and Rashmi Batra and William Miller",

year = "2011",

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doi = "10.1016/j.humpath.2010.11.021",

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T2 - A case report

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AU - Mull, Jason

AU - Batra, Rashmi

AU - Miller, William

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N2 - We present a rare case of unilateral intratesticular cystadenocarcinoma with mucinous differentiation in a 71-year-old male patient. The orchiectomy specimen revealed a 3.5-cm well to moderately differentiated cystic neoplasm with elongated fine papillary structures lined by columnar epithelium with alternating goblet and ciliated cells completely replacing the testicular parenchyma. Immunohistochemical studies showed positivity for cytokeratin 20, carcinoembryonic antigen, and mucin 2, and negativity for cytokeratin 7, mucin 5AC, vimentin, thyroid transcription factor 1, Wilms' tumor 1, and cancer antigen 125. The current case shows a focal cyst-lining component with benign appearance. Imaging studies and colonoscopy showed no evidence of other suspicious lesions. This tumor resembles morphologically to an intestinal-type ovarian surface epithelial tumor.

AB - We present a rare case of unilateral intratesticular cystadenocarcinoma with mucinous differentiation in a 71-year-old male patient. The orchiectomy specimen revealed a 3.5-cm well to moderately differentiated cystic neoplasm with elongated fine papillary structures lined by columnar epithelium with alternating goblet and ciliated cells completely replacing the testicular parenchyma. Immunohistochemical studies showed positivity for cytokeratin 20, carcinoembryonic antigen, and mucin 2, and negativity for cytokeratin 7, mucin 5AC, vimentin, thyroid transcription factor 1, Wilms' tumor 1, and cancer antigen 125. The current case shows a focal cyst-lining component with benign appearance. Imaging studies and colonoscopy showed no evidence of other suspicious lesions. This tumor resembles morphologically to an intestinal-type ovarian surface epithelial tumor.

KW - Cyst

KW - Cystadenocarcinoma

KW - Intestinal

KW - Intratesticular

KW - Mucinous

KW - Ovarian surface epithelial tumor

KW - Testicular adenocarcinoma

KW - Testis

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Mucinous cystadenocarcinoma of the testis: A case report

Abstract

Keywords

ASJC Scopus subject areas

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