@article{0ac30b10710b4a02b523e451ead566c9,
title = "MR spectroscopy detects lipid peaks in cerebrotendinous xanthomatosis",
abstract = "CTX is a rare lipid-storage disease. Novel MRS findings from 3 patients, using a short TE, were the presence of lipid peaks at 0.9 and 1.3 ppm in the depth of the cerebellar hemisphere; this might represent an additional marker of disease that is CNS-specific and noninvasive. A decrease in NAA concentration was also detected and attributed to neuroaxonal damage. One patient presented an increase in mIns concentration, pointing to gliosis and astrocytic proliferation.",
author = "Embiru{\c c}u, {E. K.} and Otaduy, {M. C.G.} and Taneja, {A. K.} and Leite, {C. C.} and Fernando Kok and Lucato, {L. T.}",
note = "Funding Information: Y-HJ has received honoraria for lectures from Sanofi-Aventis, Daiichi Sankyo, Eli Lilly, Nanosphere, and Otsuka; and research grants or support from Dong-A Pharmaceutical, Boehringer Ingelheim, Otsuka, Accumetrics, and Multiplate. PAG has received research grants, honoraria, and consultant fees from AstraZeneca, Merck, Medtronic, Lilly/Daiichi Sankyo, Sanofi Aventis/Bristol Myers, Novartis, Boston Scientific, Bayer, Accumetrics, Boehringer Ingelheim, and Johnson and Johnson. The other authors declare that they have no conflicts of interest.",
year = "2010",
month = aug,
doi = "10.3174/ajnr.A1885",
language = "English (US)",
volume = "31",
pages = "1347--1349",
journal = "American Journal of Neuroradiology",
issn = "0195-6108",
publisher = "American Society of Neuroradiology",
number = "7",
}