@article{acea00a5ebe7438a923172f76a483d0e,
title = "MOXI Is a Mitochondrial Micropeptide That Enhances Fatty Acid β-Oxidation",
abstract = "Micropeptide regulator of β-oxidation (MOXI) is encoded by a muscle-enriched RNA transcript misannotated as non-coding. MOXI localizes to the inner mitochondrial membrane where it interacts with the trifunctional protein to modulate fatty acid β-oxidation and exercise capacity.",
keywords = "fatty acid oxidation, metabolism, micropeptide, mitochondria, noncoding RNA, trifunctional protein",
author = "Makarewich, {Catherine A.} and Baskin, {Kedryn K.} and Munir, {Amir Z.} and Svetlana Bezprozvannaya and Gaurav Sharma and Chalermchai Khemtong and Shah, {Akansha M.} and McAnally, {John R.} and Malloy, {Craig R.} and Szweda, {Luke I.} and Rhonda Bassel-Duby and Olson, {Eric N.}",
note = "Funding Information: We thank J. Cabrera for graphics, H. Sadek for scientific discussion and insight, W. Tan for echocardiography, J. Karch for providing protocols and advice, and the following Core Facilities at the University of Texas Southwestern Medical Center: The Molecular Pathology Core under the direction of J. Richardson; the Electron Microscopy Core under the direction of K. Luby-Phelps; and the Proteomics Core under the direction of H. Mirzaei. This work was supported by grants from the NIH (HL-130253, HL-138426, HD-087351, DK-099653, AR-067294, P41-EB015908, and R37-HL034557), American Heart Association (16POST31100009 to K.K.B.), Fondation Leducq Networks of Excellence, and the Robert A. Welch Foundation (grant 1-0025 to E.N.O.). C.A.M. was supported by a National Heart, Lung, and Blood Institute, NIH, Ruth L. Kirschstein National Research Service Award (NRSA) (F32HL129674). ",
year = "2018",
month = jun,
day = "26",
doi = "10.1016/j.celrep.2018.05.058",
language = "English (US)",
volume = "23",
pages = "3701--3709",
journal = "Cell Reports",
issn = "2211-1247",
publisher = "Cell Press",
number = "13",
}