Monoamine Oxidase Inhibitors

P. M. Wax

doi:10.1016/B978-0-12-386454-3.00753-3

Monoamine Oxidase Inhibitors

P. M. Wax

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Monoamine oxidase inhibitors (MAOIs) were the first antidepressants marketed in the beginning of the 1950s. They were found to be associated with serious drug "drug and drug" food adverse reactions manifested by symptoms of serious hyperadrenergic and hyperserotenergic excess. They have not been used as first-line antidepressants for many years, although they are still occasionally used to treat atypical and refractory depression. Selegiline, a selective monoamine oxidase B inhibitor, is used in the treatment of Parkinson's disease and is less likely to cause similar adverse reactions.

Original language	English (US)
Title of host publication	Encyclopedia of Toxicology
Subtitle of host publication	Third Edition
Publisher	Elsevier
Pages	389-390
Number of pages	2
ISBN (Electronic)	9780123864543
ISBN (Print)	9780123864550
DOIs	https://doi.org/10.1016/B978-0-12-386454-3.00753-3
State	Published - Jan 1 2014

Keywords

Isocarboxazid
Moclobemide
Monomamine oxidase inhibitor
Phenelzine
Selegiline
Serotonin syndrome
Tranylcypromine
Tryamine

ASJC Scopus subject areas

Medicine(all)

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10.1016/B978-0-12-386454-3.00753-3

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title = "Monoamine Oxidase Inhibitors",

abstract = "Monoamine oxidase inhibitors (MAOIs) were the first antidepressants marketed in the beginning of the 1950s. They were found to be associated with serious drug {"}drug and drug{"} food adverse reactions manifested by symptoms of serious hyperadrenergic and hyperserotenergic excess. They have not been used as first-line antidepressants for many years, although they are still occasionally used to treat atypical and refractory depression. Selegiline, a selective monoamine oxidase B inhibitor, is used in the treatment of Parkinson's disease and is less likely to cause similar adverse reactions.",

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AB - Monoamine oxidase inhibitors (MAOIs) were the first antidepressants marketed in the beginning of the 1950s. They were found to be associated with serious drug "drug and drug" food adverse reactions manifested by symptoms of serious hyperadrenergic and hyperserotenergic excess. They have not been used as first-line antidepressants for many years, although they are still occasionally used to treat atypical and refractory depression. Selegiline, a selective monoamine oxidase B inhibitor, is used in the treatment of Parkinson's disease and is less likely to cause similar adverse reactions.

KW - Isocarboxazid

KW - Moclobemide

KW - Monomamine oxidase inhibitor

KW - Phenelzine

KW - Selegiline

KW - Serotonin syndrome

KW - Tranylcypromine

KW - Tryamine

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DO - 10.1016/B978-0-12-386454-3.00753-3

M3 - Chapter

AN - SCOPUS:85043260774

SN - 9780123864550

SP - 389

EP - 390

BT - Encyclopedia of Toxicology

PB - Elsevier

ER -

Monoamine Oxidase Inhibitors

Abstract

Keywords

ASJC Scopus subject areas

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