Molecular weight determination of nucleic acids and proteins

Ravi Prakash, Pramod Kumar Singh, Santosh Kumar Jatav, Ajay Kumar Gautam

Research output: Chapter in Book/Report/Conference proceedingChapter


The determination of the molecular weight of nucleic acids and proteins has found wide application in biosciences especially as it relates to the evaluation of molecular properties, separation, identification, purification, and characterization of nucleic acids and proteins. The commonly employed techniques for the determination of molecular weights (MWs) include electrophoresis, centrifugation, precipitation, chromatography, and mass spectrometry. In this chapter, authors presented in detail the MW determination of nucleic acids and proteins and the techniques employed for successful determinations.

Original languageEnglish (US)
Title of host publicationAnalytical Techniques in Biosciences
Subtitle of host publicationfrom Basics to Applications
Number of pages10
ISBN (Electronic)9780128226544
ISBN (Print)9780128227992
StatePublished - Jan 1 2022
Externally publishedYes


  • chromatography
  • DNA
  • Protein
  • RNA molecular weight

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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