Molecular rotors: synthesis and evaluation as viscosity sensors

Jeyanthy Sutharsan, Darcy Lichlyter, Nathan E. Wright, Marianna Dakanali, Mark A. Haidekker, Emmanuel A. Theodorakis

Research output: Contribution to journalArticlepeer-review

92 Scopus citations


It has been shown that compounds containing the p-N,N-dialkylaminobenzylidene cyanoacetate motif can serve as fluorescent non-mechanical viscosity sensors. These compounds, referred to as molecular rotors, belong to a class of fluorescent probes that are known to form twisted intramolecular charge-transfer complexes in the excited state. In this study we present the synthesis and spectroscopic characterization of these compounds as viscosity sensors. The effects of the molecular structure and electronic density of these rotors to the emission wavelength, fluorescence intensity, and viscosity sensitivity are discussed.

Original languageEnglish (US)
Pages (from-to)2582-2588
Number of pages7
Issue number14
StatePublished - Apr 3 2010

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


Dive into the research topics of 'Molecular rotors: synthesis and evaluation as viscosity sensors'. Together they form a unique fingerprint.

Cite this