TY - JOUR
T1 - Methods and design of the baseline survey of the neurological disorders in Salamanca (NEDISA) cohort
T2 - A population-based study in Central-Western Spain
AU - Cacho, Jesús
AU - Benito-León, Julián
AU - Louis, Elan D.
PY - 2011/2
Y1 - 2011/2
N2 - Background: To describe the design of the baseline assessment of an epidemiological study of elderly persons living in Salamanca, central-western Spain: the Neurological Diseases in Salamanca (NEDISA) study. We assessed the epidemiology of stroke, cognitive disorders, essential tremor (ET), Parkinson's disease (PD) and restless legs syndrome. Methods: In phase 1 (February 1 to May 31, 2007), 4 neurologists and 2 trained general physicians examined and performed phlebotomy on all participants. In phase 2 (June 1, 2007, to June 1, 2008), the participants were reexamined and had a complete neuropsychological assessment. Neuroimaging was performed in participants with cognitive disorders, ET and PD. Results: The registered study population consisted of 1,077 individuals, but 45 people were ineligible (address change, refusals or death), leaving a final sample of 1,032 (95.8%). The main demographic data on the 1,032 participants (408 men, 624 women) are provided. Conclusions: Most of the registered study population was enrolled, and this may have been due to the close relationship between NEDISA researchers and the general physicians in the area of study. The NEDISA study will likely improve our knowledge of prevalence rates of the neurological diseases chosen for study as well as the set of risk factors that predispose individuals in Spain to these disorders.
AB - Background: To describe the design of the baseline assessment of an epidemiological study of elderly persons living in Salamanca, central-western Spain: the Neurological Diseases in Salamanca (NEDISA) study. We assessed the epidemiology of stroke, cognitive disorders, essential tremor (ET), Parkinson's disease (PD) and restless legs syndrome. Methods: In phase 1 (February 1 to May 31, 2007), 4 neurologists and 2 trained general physicians examined and performed phlebotomy on all participants. In phase 2 (June 1, 2007, to June 1, 2008), the participants were reexamined and had a complete neuropsychological assessment. Neuroimaging was performed in participants with cognitive disorders, ET and PD. Results: The registered study population consisted of 1,077 individuals, but 45 people were ineligible (address change, refusals or death), leaving a final sample of 1,032 (95.8%). The main demographic data on the 1,032 participants (408 men, 624 women) are provided. Conclusions: Most of the registered study population was enrolled, and this may have been due to the close relationship between NEDISA researchers and the general physicians in the area of study. The NEDISA study will likely improve our knowledge of prevalence rates of the neurological diseases chosen for study as well as the set of risk factors that predispose individuals in Spain to these disorders.
KW - Elderly
KW - Epidemiology
KW - Population-based survey
UR - http://www.scopus.com/inward/record.url?scp=78651547177&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78651547177&partnerID=8YFLogxK
U2 - 10.1159/000323269
DO - 10.1159/000323269
M3 - Article
C2 - 21252583
AN - SCOPUS:78651547177
SN - 0251-5350
VL - 36
SP - 62
EP - 68
JO - Neuroepidemiology
JF - Neuroepidemiology
IS - 1
ER -