Metallic coil and N-butyl-2-cyanoacrylate for closure of pancreatic duct leak (with video)

Ara B. Sahakian, Preeth Jayaram, M. Victoria Marx, Kazuhide Matsushima, Caroline Park, James L. Buxbaum

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Background and Aims: Pancreatic fistula is a challenging yet common adverse event of partial pancreatectomy. Our objective is to determine the feasibility of endoscopic closure of a pancreatic fistula using a combination of a metallic coil and N-butyl-2-cyanoacrylate (NBCA) glue. Methods: A patient with a postoperative pancreatic stump leak recalcitrant to conservative management and pancreatic duct stent placement underwent endoscopic/fluoroscopic placement of a metallic coil in the pancreatic duct followed by injection of.5 mL NBCA and lipiodol mixture directed at the coil. The patient's clinical condition, Jackson-Pratt (JP) drain output, and pancreatic enzyme content were monitored daily after the procedure. Results: The patient's clinical condition improved. JP drain output and amylase/lipase levels progressively decreased to resolution within 7 days of the procedure. No adverse events occurred as a result of the procedure. Conclusions: Endoscopic closure of pancreatic fistula with a metallic coil and NBCA glue is feasible and may be a useful modality for treatment of refractory postpancreatectomy-related fistula.

Original languageEnglish (US)
Pages (from-to)1122-1125
Number of pages4
JournalGastrointestinal Endoscopy
Issue number4
StatePublished - Apr 2018
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology


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