Metal-catalyzed [1,2]-alkyl shift in allenyl ketones: Synthesis of multisubstituted furans

Alexander S. Dudnik, Vladimir Gevorgyan

Research output: Contribution to journalArticlepeer-review

201 Scopus citations


(Chemical Equation Presented) Even fused furans can be prepared by cycloisomerization of substituted allenyl ketones. The cascade reaction involves a [1,2]-migration of alkyl or aryl groups in allenyl ketones as the key step. Facile reaction in the presence of cationic complexes, as well as migratory aptitude in the cycloisomerization of unsymmetrically substituted allenes, strongly supports an electrophilic mechanism for this transformation.

Original languageEnglish (US)
Pages (from-to)5195-5197
Number of pages3
JournalAngewandte Chemie - International Edition
Issue number27
StatePublished - 2007
Externally publishedYes


  • Allenyl ketones
  • Furans
  • Gold
  • Lewis acids
  • Rearrangment

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)


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