TY - JOUR
T1 - Metachronous Uterine Endometrioid Adenocarcinoma and Peritoneal Mesothelioma in Lynch Syndrome
T2 - A Case Report
AU - Lu, Yuxin
AU - Milchgrub, Sara
AU - Khatri, Gaurav
AU - Gopal, Purva
PY - 2017/5/1
Y1 - 2017/5/1
N2 - Lynch syndrome is a hereditary disease with germline mutation in a DNA mismatch repair gene, most often presenting with colorectal and/or endometrial carcinomas; however, the spectrum of Lynch syndrome-associated tumors is expanding. In this article, we report a case of a primary peritoneal epithelioid mesothelioma that developed in a Lynch syndrome patient 10 months after diagnosis of uterine endometrioid adenocarcinoma. To our knowledge, this is the first reported case of a Lynch syndrome patient with metachronous uterine endometrioid adenocarcinoma and primary peritoneal mesothelioma.
AB - Lynch syndrome is a hereditary disease with germline mutation in a DNA mismatch repair gene, most often presenting with colorectal and/or endometrial carcinomas; however, the spectrum of Lynch syndrome-associated tumors is expanding. In this article, we report a case of a primary peritoneal epithelioid mesothelioma that developed in a Lynch syndrome patient 10 months after diagnosis of uterine endometrioid adenocarcinoma. To our knowledge, this is the first reported case of a Lynch syndrome patient with metachronous uterine endometrioid adenocarcinoma and primary peritoneal mesothelioma.
KW - endometrioid adenocarcinoma
KW - Lynch syndrome
KW - peritoneal mesothelioma
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U2 - 10.1177/1066896916680745
DO - 10.1177/1066896916680745
M3 - Article
C2 - 27903930
AN - SCOPUS:85018337370
SN - 1066-8969
VL - 25
SP - 253
EP - 257
JO - International Journal of Surgical Pathology
JF - International Journal of Surgical Pathology
IS - 3
ER -