Metabolic syndrome update

Scott M Grundy

doi:10.1016/j.tcm.2015.10.004

Metabolic syndrome update

Scott M Grundy

Research output: Contribution to journal › Review article › peer-review

595 Scopus citations

Abstract

The metabolic syndrome is a multiplex risk factor for atherosclerotic cardiovascular disease and type 2 diabetes. It is composed of atherogenic dyslipidemia, elevated blood pressure, insulin resistance and elevated glucose, a pro-thrombotic state, and a pro-inflammatory state. Excess energy intake and concomitant obesity are the major drivers of the syndrome. Lifestyle intervention can reverse metabolic risk factors, but at times, drug therapies or bariatric surgery may be required to control more overt risk factors.

Original language	English (US)
Pages (from-to)	364-373
Number of pages	10
Journal	Trends in Cardiovascular Medicine
Volume	26
Issue number	4
DOIs	https://doi.org/10.1016/j.tcm.2015.10.004
State	Published - May 1 2016

Keywords

Diabetes
Dyslipidemia
Hypertension
Metabolic syndrome
Nutrition
Obesity

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.tcm.2015.10.004

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AB - The metabolic syndrome is a multiplex risk factor for atherosclerotic cardiovascular disease and type 2 diabetes. It is composed of atherogenic dyslipidemia, elevated blood pressure, insulin resistance and elevated glucose, a pro-thrombotic state, and a pro-inflammatory state. Excess energy intake and concomitant obesity are the major drivers of the syndrome. Lifestyle intervention can reverse metabolic risk factors, but at times, drug therapies or bariatric surgery may be required to control more overt risk factors.

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KW - Dyslipidemia

KW - Hypertension

KW - Metabolic syndrome

KW - Nutrition

KW - Obesity

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Metabolic syndrome update

Abstract

Keywords

ASJC Scopus subject areas

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