Metabolic syndrome update

Research output: Contribution to journalReview articlepeer-review

477 Scopus citations


The metabolic syndrome is a multiplex risk factor for atherosclerotic cardiovascular disease and type 2 diabetes. It is composed of atherogenic dyslipidemia, elevated blood pressure, insulin resistance and elevated glucose, a pro-thrombotic state, and a pro-inflammatory state. Excess energy intake and concomitant obesity are the major drivers of the syndrome. Lifestyle intervention can reverse metabolic risk factors, but at times, drug therapies or bariatric surgery may be required to control more overt risk factors.

Original languageEnglish (US)
Pages (from-to)364-373
Number of pages10
JournalTrends in Cardiovascular Medicine
Issue number4
StatePublished - May 1 2016


  • Diabetes
  • Dyslipidemia
  • Hypertension
  • Metabolic syndrome
  • Nutrition
  • Obesity

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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