Medical Management of Asymptomatic Carotid Artery Stenosis

Aaron W. Aday; Joshua A. Beckman

doi:10.1016/j.pcad.2017.05.008

Medical Management of Asymptomatic Carotid Artery Stenosis

Aaron W. Aday, Joshua A. Beckman

Research output: Contribution to journal › Review article › peer-review

24 Scopus citations

Abstract

Carotid artery atherosclerosis is a major risk factor for both stroke and cardiovascular disease. Appropriate management of asymptomatic patients with carotid artery stenosis (CAS) remains unclear. Although several randomized clinical trials support revascularization in asymptomatic patients with severe CAS to reduce stroke risk, the participants in these trials did not receive optimal medical therapy (OMT) by today's standards. For many individuals, medical therapy may provide excellent risk reduction without the periprocedural risk of endarterectomy or stenting. In this review, we discuss the risk factors for CAS and stroke and examine the data for each component of OMT in these patients.

Original language	English (US)
Pages (from-to)	585-590
Number of pages	6
Journal	Progress in Cardiovascular Diseases
Volume	59
Issue number	6
DOIs	https://doi.org/10.1016/j.pcad.2017.05.008
State	Published - May 2017
Externally published	Yes

Keywords

Atherosclerosis
Carotid artery stenosis
Hypertension
Statin
Stroke

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.pcad.2017.05.008

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title = "Medical Management of Asymptomatic Carotid Artery Stenosis",

abstract = "Carotid artery atherosclerosis is a major risk factor for both stroke and cardiovascular disease. Appropriate management of asymptomatic patients with carotid artery stenosis (CAS) remains unclear. Although several randomized clinical trials support revascularization in asymptomatic patients with severe CAS to reduce stroke risk, the participants in these trials did not receive optimal medical therapy (OMT) by today's standards. For many individuals, medical therapy may provide excellent risk reduction without the periprocedural risk of endarterectomy or stenting. In this review, we discuss the risk factors for CAS and stroke and examine the data for each component of OMT in these patients.",

keywords = "Atherosclerosis, Carotid artery stenosis, Hypertension, Statin, Stroke",

author = "Aday, {Aaron W.} and Beckman, {Joshua A.}",

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year = "2017",

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T1 - Medical Management of Asymptomatic Carotid Artery Stenosis

AU - Aday, Aaron W.

AU - Beckman, Joshua A.

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N2 - Carotid artery atherosclerosis is a major risk factor for both stroke and cardiovascular disease. Appropriate management of asymptomatic patients with carotid artery stenosis (CAS) remains unclear. Although several randomized clinical trials support revascularization in asymptomatic patients with severe CAS to reduce stroke risk, the participants in these trials did not receive optimal medical therapy (OMT) by today's standards. For many individuals, medical therapy may provide excellent risk reduction without the periprocedural risk of endarterectomy or stenting. In this review, we discuss the risk factors for CAS and stroke and examine the data for each component of OMT in these patients.

AB - Carotid artery atherosclerosis is a major risk factor for both stroke and cardiovascular disease. Appropriate management of asymptomatic patients with carotid artery stenosis (CAS) remains unclear. Although several randomized clinical trials support revascularization in asymptomatic patients with severe CAS to reduce stroke risk, the participants in these trials did not receive optimal medical therapy (OMT) by today's standards. For many individuals, medical therapy may provide excellent risk reduction without the periprocedural risk of endarterectomy or stenting. In this review, we discuss the risk factors for CAS and stroke and examine the data for each component of OMT in these patients.

KW - Atherosclerosis

KW - Carotid artery stenosis

KW - Hypertension

KW - Statin

KW - Stroke

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DO - 10.1016/j.pcad.2017.05.008

M3 - Review article

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SN - 0033-0620

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EP - 590

JO - Progress in Cardiovascular Diseases

JF - Progress in Cardiovascular Diseases

IS - 6

ER -

Medical Management of Asymptomatic Carotid Artery Stenosis

Abstract

Keywords

ASJC Scopus subject areas

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