Mediator Comes Out from the Shadows

Ronald C. Conaway, Joan Weliky Conaway

Research output: Contribution to journalShort surveypeer-review

2 Scopus citations


In this issue of Structure, Cai et al. describe a substantially improved cryo-EM reconstruction of the multisubunit Mediator of transcriptional regulation. The improved Mediator structural model highlights the remarkable conformational flexibility of Mediator and reveals previously unrecognized features of Mediator modules.

Original languageEnglish (US)
Pages (from-to)485-486
Number of pages2
Issue number4
StatePublished - Apr 15 2009
Externally publishedYes

ASJC Scopus subject areas

  • Structural Biology
  • Molecular Biology


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