TY - JOUR
T1 - Mechanistic insights into the gold-catalyzed cycloisomerization of bromoallenyl ketones
T2 - Ligand-controlled regioselectivity
AU - Xia, Yuanzhi
AU - Dudnik, Alexander S.
AU - Gevorgyan, Vladimir
AU - Li, Yahong
PY - 2008/6/4
Y1 - 2008/6/4
N2 - Through computational and experimental studies, the mechanisms of gold-catalyzed cycloisomerization of bromoallenyl ketones in toluene have been elucidated. The divergent 1,2-migrations for the Au(I)- and Au(III)-catalyzed reactions have been investigated, and the results confirmed that the regiochemistry is ligand-dependent in cases of Au(PR3)L (L = Cl, OTf, BF4, and SbF6) catalysts.
AB - Through computational and experimental studies, the mechanisms of gold-catalyzed cycloisomerization of bromoallenyl ketones in toluene have been elucidated. The divergent 1,2-migrations for the Au(I)- and Au(III)-catalyzed reactions have been investigated, and the results confirmed that the regiochemistry is ligand-dependent in cases of Au(PR3)L (L = Cl, OTf, BF4, and SbF6) catalysts.
UR - http://www.scopus.com/inward/record.url?scp=44449174624&partnerID=8YFLogxK
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U2 - 10.1021/ja802144t
DO - 10.1021/ja802144t
M3 - Article
C2 - 18461941
AN - SCOPUS:44449174624
SN - 0002-7863
VL - 130
SP - 6940
EP - 6941
JO - Journal of the American Chemical Society
JF - Journal of the American Chemical Society
IS - 22
ER -