Management of benign prostatic hyperplasia

M. Barry, Claus Roehrborn

Research output: Contribution to journalReview articlepeer-review

34 Scopus citations


Benign prostatic hyperplasia (BPH) is a common cause of morbidity among older men. Primary care physicians need to develop expertise in its management. The causes of BPH are unknown; aging and the presence of male androgens are the dominant risk factors. Obtaining a medical history is a key step in assessing whether lower urinary tract symptoms are due to BPH or to some other process. A reliable and valid seven-item questionnaire has been developed to objectively assess symptom severity. A focused physical examination including a digital rectal exam should be performed, as well as a urinalysis and serum creatinine. Optional tests include uroflowmetry, post-void residual urine, and prostate-specific antigen measurements. BPH is treated primarily to improve the quality, rather than increase the quantity, of life. Optimal decisions about treatment are best made by a clinician and an informed patient working together.

Original languageEnglish (US)
Pages (from-to)177-189
Number of pages13
JournalAnnual review of medicine
StatePublished - 1997


  • Adrenergic alpha-antagonists
  • Finasteride
  • Prostate-specific antigen
  • Prostatectomy
  • Prostatic hyperplasia

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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