Malignant Female Adnexal Tumor of Probable Wolffian Origin: Case Report and Literature Review

Shuhui Hong, Jing Cui, Li Li, Joseph Buscema, Casandra Liggins, Wenxin Zheng

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations

Abstract

Although most female adnexal tumors of probable Wolffian origin have a benign biologic behavior, occasional cases have exhibited malignant potential. We encountered a 50-yr-old woman with an uncommon female adnexal tumors of probable Wolffian origin, which involved bilateral ovaries, invaded the ipsilateral fallopian tube, and extended to the uterine serosa. The initial histopathologic presentation caused significant confusion in pathologic diagnosis. Multiple differential diagnoses including ovarian endometrioid carcinoma, Sertoli cell tumor, and metastasis from nongynecologic organs were considered. After careful examination of the histologic findings and a thorough investigation with multiple immunohistochemical stains, the diagnosis was ultimately established. A literature review on female adnexal tumors of probable Wolffian origin including a malignant form is presented.

Original languageEnglish (US)
Pages (from-to)331-337
Number of pages7
JournalInternational Journal of Gynecological Pathology
Volume37
Issue number4
DOIs
StatePublished - 2018

Keywords

  • Female adnexal tumor
  • Ovarian cancer
  • Wolffian tumor

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Obstetrics and Gynecology

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