Malarial dihydroorotate dehydrogenase: Substrate and inhibitor specificity

Medicine & Life Sciences

• dihydroorotate dehydrogenase 100%
• Substrate Specificity 66%
• 4,5-dihydroorotic acid 37%
• pyrimidine 36%
• Enzyme Inhibitors 33%
• Enzymes 32%
• Flavin Mononucleotide 29%
• Terpenes 24%
• 2,2'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)diimino)bis-benzoic acid 22%
• dichloroallyl lawsone 22%
• 2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone 19%
• ubiquinone 6 19%
• Inhibitory Concentration 50 17%
• A 771726 17%
• Parasites 16%
• Pyrimidines 14%
• Vitamin K 3 13%
• Ubiquinone 13%
• Antimalarials 10%
• Catalytic Domain 8%
• Mitochondria 8%
• Escherichia coli 6%
• Membranes 5%

Chemical Compounds

• Dihydroorotate 94%
• Pyrimidine 30%
• Cofactor 23%
• Isoprenoid 21%
• Biosynthesis 14%
• Lawsone 13%
• Orotate 13%
• Ubiquinone 10%
• Antimalarial 10%
• Vitamin 8%
• Oxidation Reaction 7%
• Length 5%
• pH Value 3%