Lock and key to transcription: σ-DNA interaction

Xin Liu, David A. Bushnell, Roger D. Kornberg

Research output: Contribution to journalShort surveypeer-review

18 Scopus citations


How does RNA polymerase recognize a promoter in duplex DNA? How are the DNA strands pried apart to enable RNA synthesis? A crystal structure by Feklistov and Darst unexpectedly reveals that these two processes are interconnected.

Original languageEnglish (US)
Pages (from-to)1218-1219
Number of pages2
Issue number6
StatePublished - Dec 9 2011

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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