Several human B-cell immunodeficiencies result from mutations in signal transducing molecules. The past year has seen significant advances in our understanding of how these molecules are integrated into B cell signaling pathways. The phenotypes of mice deficient in several of these genes have revealed species-specific differences in the requirements for early B cell development.
|Original language||English (US)|
|Number of pages||5|
|Journal||Current Opinion in Immunology|
|State||Published - Aug 1996|
ASJC Scopus subject areas
- Immunology and Allergy