LED-based hyperspectral endoscopic imaging

Naeeme Modir, Maysam Shahedi, James Dormer, Ling Ma, Mohammadaref Ghaderi, Shashank Sirsi, Yi Shing Lisa Cheng, Baowei Fei

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations


Hyperspectral endoscopy can offer multiple advantages as compared to conventional endoscopy. Our goal is to design and develop a real-Time hyperspectral endoscopic imaging system for the diagnosis of gastrointestinal (GI) tract cancers using a micro-LED array as an in-situ illumination source. The wavelengths of the system range from ultraviolet to visible and near infrared. To evaluate the use of the LED array for hyperspectral imaging, we designed a prototype system and conducted ex vivo experiments using normal and cancerous tissues of mice, chicken, and sheep. We compared the results of our LED-based approach with our reference hyperspectral camera system. The results confirm the similarity between the LED-based hyperspectral imaging system and the reference HSI camera. Our LED-based hyperspectral imaging system can be used not only as an endoscope but also as a laparoscopic or handheld devices for cancer detection and surgery.

Original languageEnglish (US)
Title of host publicationOptical Biopsy XX
Subtitle of host publicationToward Real-Time Spectroscopic Imaging and Diagnosis
EditorsRobert R. Alfano, Stavros G. Demos, Angela B. Seddon
ISBN (Electronic)9781510647794
StatePublished - 2022
EventOptical Biopsy XX: Toward Real-Time Spectroscopic Imaging and Diagnosis 2022 - Virtual, Online
Duration: Feb 20 2022Feb 24 2022

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferenceOptical Biopsy XX: Toward Real-Time Spectroscopic Imaging and Diagnosis 2022
CityVirtual, Online


  • Cancer
  • Endoscopy, laparoscope
  • FPGA
  • Handheld device
  • Hyperspectral imaging
  • Micro-LED
  • Surgery

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging


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