LDL cholesterol: Its regulation and manipulation

J. M. Dietschy

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Elevated plasma LDL cholesterol concentrations result primarily from two mechanisms: LDL overproduction and loss of hepatic receptor-dependent LDL removal. This knowledge can be used to lower plasma cholesterol and thereby retard or even reverse atherosclerosis. Pharmacologic agents are useful, as are dietary approaches.

Original languageEnglish (US)
Pages (from-to)67-78
Number of pages12
JournalHospital Practice
Issue number6
StatePublished - 1990

ASJC Scopus subject areas

  • Medicine(all)


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