@inproceedings{08a9818e42b24a92b00782c53f3ee57d,
title = "Laminar flow induces endothelial cell growth arrest through p53 phosphorylation and stabilization",
abstract = "We investigated the role of p53 in mediating the laminar flow-induced growth arrest in endothelial cells (ECs). c-Jun N-terminal kinase (JNK) activity induced by laminar flow is able to phosphorylate p53, an event which leads to the stabilization of p53. We also found that laminar flow caused an increase in the protein level of the exogenous HA-p53 in ECs. This increased p53 level would suppress EC proliferation.",
author = "Benjamin Chen and Suli Yuan and Hsu, {Pin Pin} and Shyy, {John Y J} and Shu Chien",
year = "1999",
language = "English (US)",
isbn = "0780356756",
series = "Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings",
publisher = "IEEE",
pages = "7",
booktitle = "Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings",
note = "Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) ; Conference date: 13-10-1999 Through 16-10-1999",
}