Lactic Acidosis in Oat Cell Carcinoma With Extensive Hepatic Metastases

S. J. Spechler; A. L. Esposito; R. S. Koff; W. K. Hong

doi:10.1001/archinte.1978.03630360045020

Lactic Acidosis in Oat Cell Carcinoma With Extensive Hepatic Metastases

S. J. Spechler, A. L. Esposito, R. S. Koff, W. K. Hong

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Abstract

Lactic acidosis has been described in patients with leukemia and lymphoma, but its occurrence in other malignant diseases is not documented. We treated two patients with oat cell carcinoma of the lung and extensive liver metastases in whom lactic acidosis developed. Tumor-induced hepatic dysfunction appeared to be a major factor in the pathogenesis of the lactic acidosis observed in these patients.

Original language	English (US)
Pages (from-to)	1663-1664
Number of pages	2
Journal	Archives of Internal Medicine
Volume	138
Issue number	11
DOIs	https://doi.org/10.1001/archinte.1978.03630360045020
State	Published - Nov 1978

ASJC Scopus subject areas

Internal Medicine

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10.1001/archinte.1978.03630360045020

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abstract = "Lactic acidosis has been described in patients with leukemia and lymphoma, but its occurrence in other malignant diseases is not documented. We treated two patients with oat cell carcinoma of the lung and extensive liver metastases in whom lactic acidosis developed. Tumor-induced hepatic dysfunction appeared to be a major factor in the pathogenesis of the lactic acidosis observed in these patients.",

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AB - Lactic acidosis has been described in patients with leukemia and lymphoma, but its occurrence in other malignant diseases is not documented. We treated two patients with oat cell carcinoma of the lung and extensive liver metastases in whom lactic acidosis developed. Tumor-induced hepatic dysfunction appeared to be a major factor in the pathogenesis of the lactic acidosis observed in these patients.

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Lactic Acidosis in Oat Cell Carcinoma With Extensive Hepatic Metastases

Abstract

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