Lactic Acidosis in Oat Cell Carcinoma With Extensive Hepatic Metastases

S. J. Spechler, A. L. Esposito, R. S. Koff, W. K. Hong

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


Lactic acidosis has been described in patients with leukemia and lymphoma, but its occurrence in other malignant diseases is not documented. We treated two patients with oat cell carcinoma of the lung and extensive liver metastases in whom lactic acidosis developed. Tumor-induced hepatic dysfunction appeared to be a major factor in the pathogenesis of the lactic acidosis observed in these patients.

Original languageEnglish (US)
Pages (from-to)1663-1664
Number of pages2
JournalArchives of Internal Medicine
Issue number11
StatePublished - Nov 1978

ASJC Scopus subject areas

  • Internal Medicine


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