KERATINIZATION OF THE BULBAR CONJUNCTIVAL EPITHELIUM IN SUPERIOR LIMBIC KERATOCONJUNCTIVITIS IN HUMANS: An Electron Microscopic Study

H. B. Collin; P. C. Donshik; C. S. Foster; S. A. Boruchoff; Harrison D Cavanagh

doi:10.1111/j.1755-3768.1978.tb01366.x

KERATINIZATION OF THE BULBAR CONJUNCTIVAL EPITHELIUM IN SUPERIOR LIMBIC KERATOCONJUNCTIVITIS IN HUMANS: An Electron Microscopic Study

H. B. Collin, P. C. Donshik, C. S. Foster, S. A. Boruchoff, Harrison D Cavanagh

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

A prominent histological feature of superior limbic keratoconjunctivitis is the presence of keratinization of the superior bulbar conjunctiva. Ultra‐structurally the affected conjunctival epithelium shows all of the characteristics of keratinization as described in skin. There is a superficial layer of horny cells with reduced organelles and thickened cell membrane. In the intermediate layers, the cells contain an increased number of cytoplasmic filaments which are sometimes aggregated into dense masses, kera‐tohyalin granules, both in the cytoplasm and in the nucleus, membrane coating granules, lysosomes and various other types of membranous structures. 1978 Institution Acta Ophthalmologica Scandinavica

Original language	English (US)
Pages (from-to)	531-543
Number of pages	13
Journal	Acta Ophthalmologica
Volume	56
Issue number	4
DOIs	https://doi.org/10.1111/j.1755-3768.1978.tb01366.x
State	Published - Aug 1978

Keywords

conjunctivitis
electron microscopy
keratinization
keratohyalin
superior limbic keratoconjunctivitis

ASJC Scopus subject areas

Ophthalmology

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10.1111/j.1755-3768.1978.tb01366.x

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title = "KERATINIZATION OF THE BULBAR CONJUNCTIVAL EPITHELIUM IN SUPERIOR LIMBIC KERATOCONJUNCTIVITIS IN HUMANS: An Electron Microscopic Study",

abstract = "A prominent histological feature of superior limbic keratoconjunctivitis is the presence of keratinization of the superior bulbar conjunctiva. Ultra‐structurally the affected conjunctival epithelium shows all of the characteristics of keratinization as described in skin. There is a superficial layer of horny cells with reduced organelles and thickened cell membrane. In the intermediate layers, the cells contain an increased number of cytoplasmic filaments which are sometimes aggregated into dense masses, kera‐tohyalin granules, both in the cytoplasm and in the nucleus, membrane coating granules, lysosomes and various other types of membranous structures. 1978 Institution Acta Ophthalmologica Scandinavica",

keywords = "conjunctivitis, electron microscopy, keratinization, keratohyalin, superior limbic keratoconjunctivitis",

author = "Collin, {H. B.} and Donshik, {P. C.} and Foster, {C. S.} and Boruchoff, {S. A.} and Cavanagh, {Harrison D}",

year = "1978",

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T2 - An Electron Microscopic Study

AU - Collin, H. B.

AU - Donshik, P. C.

AU - Foster, C. S.

AU - Boruchoff, S. A.

AU - Cavanagh, Harrison D

PY - 1978/8

Y1 - 1978/8

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AB - A prominent histological feature of superior limbic keratoconjunctivitis is the presence of keratinization of the superior bulbar conjunctiva. Ultra‐structurally the affected conjunctival epithelium shows all of the characteristics of keratinization as described in skin. There is a superficial layer of horny cells with reduced organelles and thickened cell membrane. In the intermediate layers, the cells contain an increased number of cytoplasmic filaments which are sometimes aggregated into dense masses, kera‐tohyalin granules, both in the cytoplasm and in the nucleus, membrane coating granules, lysosomes and various other types of membranous structures. 1978 Institution Acta Ophthalmologica Scandinavica

KW - conjunctivitis

KW - electron microscopy

KW - keratinization

KW - keratohyalin

KW - superior limbic keratoconjunctivitis

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KERATINIZATION OF THE BULBAR CONJUNCTIVAL EPITHELIUM IN SUPERIOR LIMBIC KERATOCONJUNCTIVITIS IN HUMANS: An Electron Microscopic Study

Abstract

Keywords

ASJC Scopus subject areas

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