Is aspect ratio a reliable predictor of intracranial aneurysm rupture?

Ali Nader-Sepahi, Miguel Casimiro, Jon Sen, Neil D. Kitchen, Robert A. Solomon, Seppo Juvela, Juha Hernesniemi, Atos Alves De Sousa, H. Hunt Batjer

Research output: Contribution to journalArticlepeer-review

125 Scopus citations


OBJECTIVE: This study was undertaken to assess the reliability of the aspect ratio (AR) (i.e., aneurysm depth to aneurysm neck) in predicting aneurysm rupture. It has been shown that the AR is a key factor in predicting intraaneurysmal blood flow and aneurysm rupture. METHODS: Seventy-five patients with subarachnoid hemorrhage and multiple aneurysms were studied. The sizes of the aneurysms and their ARs were determined by examining the angiographic films. By comparing the difference between ruptured and unruptured aneurysms in the same individual, each patient in effect served as his or her own control. Each ruptured aneurysm was confirmed during surgery. RESULTS: There were 75 ruptured and 107 unruptured aneurysms. The mean AR was 2.70 for ruptured aneurysms, compared with 1.8 for unruptured aneurysms. This difference between the ARs was statistically significant (P < 0.001). The difference in aneurysm sizes in the two groups also was significant (P < 0.001). CONCLUSION: AR on its own is as reliable a variable as the size of the aneurysm for predicting aneurysm rupture.

Original languageEnglish (US)
Pages (from-to)1343-1348
Number of pages6
Issue number6
StatePublished - Jun 2004


  • Aneurysm size
  • Aspect ratio
  • Risk of rupture

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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