Investigation of imaging properties for submillimeter rectangular pinholes

Dan Xia, Stephen C. Moore, Mi Ae Park, Morgan Cervo, Scott D. Metzler

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Purpose: Recently, a multipinhole collimator with inserts that have both rectangular apertures and rectangular fields of view (FOVs) has been proposed for SPECT imaging since it can tile the projection onto the detector efficiently and the FOVs in transverse and axial directions become separable. The purpose of this study is to investigate the image properties of rectangular-aperture pinholes with submillimeter apertures sizes. Methods: In this work, the authors have conducted sensitivity and FOV experiments for 18 replicates of a prototype insert fabricated in platinum/iridium (Pt/Ir) alloy with submillimeter square-apertures. A sinqθ fit to the experimental sensitivity has been performed for these inserts. For the FOV measurement, the authors have proposed a new formula to calculate the projection intensity of a flood image on the detector, taking into account the penumbra effect. By fitting this formula to the measured projection data, the authors obtained the acceptance angles. Results: The mean (standard deviation) of fitted sensitivity exponents q and effective edge lengths we were, respectively, 10.8 (1.8) and 0.38 mm (0.02 mm), which were close to the values, 7.84 and 0.396 mm, obtained from Monte Carlo calculations using the parameters of the designed inserts. For the FOV measurement, the mean (standard deviation) of the transverse and axial acceptances were 35.0° (1.2°) and 30.5° (1.6°), which are in good agreement with the designed values (34.3° and 29.9°). Conclusions: These results showed that the physical properties of the fabricated inserts with submillimeter aperture size matched our design well.

Original languageEnglish (US)
Pages (from-to)6933-6944
Number of pages12
JournalMedical physics
Issue number12
StatePublished - Dec 1 2015
Externally publishedYes


  • high-resolution
  • pinhole
  • small-animal

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging


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