Intravascular membrane oxygenator and carbon dioxide removal devices: A review of performance and improvements

Joseph B. Zwischenberger; Weike Tao; Akhil Bidani

doi:10.1097/00002480-199901000-00010

Intravascular membrane oxygenator and carbon dioxide removal devices: A review of performance and improvements

Joseph B. Zwischenberger, Weike Tao, Akhil Bidani

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

Intravascular oxygenator and carbon dioxide removal device (IVOX) was developed to enhance CO₂ removal without the need for extracorporeal circulation or blood transfusion. By allowing the blood pCO₂ to rise gradually, the CO₂ excretion by IVOX can be linearly increased in a 1:1 relationships. Increased surface area with more fibers and enhanced mixing by increased fiber crimping in new prototypes of IVOX significantly decreased CO₂ removal. With improved design and patient management, clinically meaningful gas exchange and reduction in mechanical ventilatory support may be achieved during treatment of severe respiratory failure.

Original language	English (US)
Pages (from-to)	41-46
Number of pages	6
Journal	ASAIO Journal
Volume	45
Issue number	1
DOIs	https://doi.org/10.1097/00002480-199901000-00010
State	Published - Jan 1 1999

ASJC Scopus subject areas

Biophysics
Bioengineering
Biomaterials
Biomedical Engineering

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10.1097/00002480-199901000-00010

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Intravascular membrane oxygenator and carbon dioxide removal devices: A review of performance and improvements

Abstract

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