Initiation of human parturition: VIII. Metabolism of progesterone by fetal membranes of early and late human gestation

L. Milewich; N. F. Gant; B. E. Schwarz; P. C. MacDonald

Initiation of human parturition: VIII. Metabolism of progesterone by fetal membranes of early and late human gestation

L. Milewich, N. F. Gant, B. E. Schwarz, P. C. MacDonald

Research output: Contribution to journal › Article › peer-review

Abstract

A decreased rate of progesterone metabolism is detected in human fetal membranes several weeks preceding normal parturition at term. A 10- to 20-fold decrease in 20α-hydroxysteroid oxidoreductase activity and a 2- to 6-fold decrease in 5α-reductase activity are observed in human amnion and chorion laeve after 33 weeks' gestation.

Original language	English (US)
Pages (from-to)	45-48
Number of pages	4
Journal	Obstetrics and gynecology
Volume	50
Issue number	1
State	Published - Jul 1977

ASJC Scopus subject areas

Obstetrics and Gynecology

Cite this

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title = "Initiation of human parturition: VIII. Metabolism of progesterone by fetal membranes of early and late human gestation",

abstract = "A decreased rate of progesterone metabolism is detected in human fetal membranes several weeks preceding normal parturition at term. A 10- to 20-fold decrease in 20α-hydroxysteroid oxidoreductase activity and a 2- to 6-fold decrease in 5α-reductase activity are observed in human amnion and chorion laeve after 33 weeks' gestation.",

author = "L. Milewich and Gant, {N. F.} and Schwarz, {B. E.} and MacDonald, {P. C.}",

year = "1977",

month = jul,

language = "English (US)",

volume = "50",

pages = "45--48",

journal = "Obstetrics and gynecology",

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publisher = "Lippincott Williams and Wilkins",

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AU - Milewich, L.

AU - Gant, N. F.

AU - Schwarz, B. E.

AU - MacDonald, P. C.

PY - 1977/7

Y1 - 1977/7

N2 - A decreased rate of progesterone metabolism is detected in human fetal membranes several weeks preceding normal parturition at term. A 10- to 20-fold decrease in 20α-hydroxysteroid oxidoreductase activity and a 2- to 6-fold decrease in 5α-reductase activity are observed in human amnion and chorion laeve after 33 weeks' gestation.

AB - A decreased rate of progesterone metabolism is detected in human fetal membranes several weeks preceding normal parturition at term. A 10- to 20-fold decrease in 20α-hydroxysteroid oxidoreductase activity and a 2- to 6-fold decrease in 5α-reductase activity are observed in human amnion and chorion laeve after 33 weeks' gestation.

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M3 - Article

C2 - 876521

AN - SCOPUS:0017710944

SN - 0029-7844

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IS - 1

ER -

Initiation of human parturition: VIII. Metabolism of progesterone by fetal membranes of early and late human gestation

Abstract

ASJC Scopus subject areas

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