Inhibition of cholesterol synthesis with compactin renders growth of cultured cells dependent on the low density lipoprotein receptor

Medicine & Life Sciences

• mevastatin 100%
• LDL Receptors 69%
• LDL Lipoproteins 61%
• Cultured Cells 50%
• Cholesterol 44%
• Growth 30%
• Cricetulus 19%
• Ovary 10%
• 3-hydroxy-3-methylglutaryl-coenzyme A 7%
• Protamines 7%
• HDL Lipoproteins 6%
• Acetylation 6%
• Lysosomes 6%
• Endocytosis 6%
• Lipoproteins 5%
• Oxidoreductases 5%
• LDL Cholesterol 5%
• Carrier Proteins 5%
• Lymphoma 5%
• Homeostasis 4%
• Cell Line 3%
• Lung 3%
• Serum 2%
• Pharmaceutical Preparations 2%

Chemical Compounds

• Cholesterol 53%
• High-Density Lipoprotein 5%
• Coenzyme A 4%
• Lipoprotein 4%
• Mammalian Cell 4%
• Acetylation 4%
• Block Like Crystal 2%
• Plasma 2%
• Drug 2%
• Protein 1%