TY - JOUR
T1 - Influence of diabetes on long-term outcome among unselected patients with acute coronary events
AU - Svensson, Ann Marie
AU - Abrahamsson, Putte
AU - McGuire, Darren K
AU - Dellborg, Mikael
N1 - Funding Information:
We are indebted to the staff at the CCU at Östra Hospital in Göteborg, Sweden for the data management. This study was supported by grants from the Swedish Heart–Lung Foundation. The paper has been presented at ESC Congress, 30 August–3 September 2003, in Vienna, Austria and AHA Congress, 9–12 November 2003 in Orlando, Florida, USA.
PY - 2004
Y1 - 2004
N2 - Objective - The aims of this study were to investigate the prognostic influence of diabetes after an episode of unstable angina pectoris or non-Q-wave myocardial infarction (MI) and to investigate whether diabetes is independently associated with increased short- and long-term mortality risk following these episodes. Design - Consecutive patients with a diagnosis of unstable angina pectoris or non-Q-wave MI, admitted to the Coronary Care Unit at Ö stra Hospital, Göteborg, Sweden during 1988-1998 were included. The primary endpoint was 2-year mortality collected from the Swedish cause-specific mortality register. Results - The study included 4341 patients, 722 (17%) had diabetes. Diabetes was associated with increased mortality during initial hospitalization (10.2% vs 5.7%, p < 0.0001), after 30 days (13% vs 7.5%, p < 0.0001), and at 2 years (33.7% vs 20.2%, p < 0.0001). After adjustment for potentially confounding factors, diabetes remained an independent predictor of 2-year mortality following unstable coronary syndromes, the hazard ratio (HR) of death (HR = 1.6; 95% CI 1.4-1.9). Conclusions - Among patients with unstable coronary syndromes, diabetes is an independent risk factor associated with increased mortality during hospitalization, short- and long-term follow-up.
AB - Objective - The aims of this study were to investigate the prognostic influence of diabetes after an episode of unstable angina pectoris or non-Q-wave myocardial infarction (MI) and to investigate whether diabetes is independently associated with increased short- and long-term mortality risk following these episodes. Design - Consecutive patients with a diagnosis of unstable angina pectoris or non-Q-wave MI, admitted to the Coronary Care Unit at Ö stra Hospital, Göteborg, Sweden during 1988-1998 were included. The primary endpoint was 2-year mortality collected from the Swedish cause-specific mortality register. Results - The study included 4341 patients, 722 (17%) had diabetes. Diabetes was associated with increased mortality during initial hospitalization (10.2% vs 5.7%, p < 0.0001), after 30 days (13% vs 7.5%, p < 0.0001), and at 2 years (33.7% vs 20.2%, p < 0.0001). After adjustment for potentially confounding factors, diabetes remained an independent predictor of 2-year mortality following unstable coronary syndromes, the hazard ratio (HR) of death (HR = 1.6; 95% CI 1.4-1.9). Conclusions - Among patients with unstable coronary syndromes, diabetes is an independent risk factor associated with increased mortality during hospitalization, short- and long-term follow-up.
KW - Angina pectoris
KW - Diabetes mellitus
KW - Myocardial infarction
KW - Prognosis
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U2 - 10.1080/14017430410016297
DO - 10.1080/14017430410016297
M3 - Article
C2 - 15553934
AN - SCOPUS:4444301118
SN - 1401-7431
VL - 38
SP - 229
EP - 234
JO - Scandinavian Cardiovascular Journal
JF - Scandinavian Cardiovascular Journal
IS - 4
ER -