Infection: A Perilous Complication of a Closure Device

The ability to achieve earlier hemostasis and comfort with percutaneous vascular closure devices (VCD) without major complications has contributed to the increase of their use. The use of VCD has been associated with different complications including access-site/femoral artery infection. We describe herein an illustrative case of a 47-year-old female patient with abnormal nuclear stress test, who developed a suturebased VCD-related infection following diagnostic coronary angiography. The patient was empirically treated with broad-spectrum antibiotics, early wound exploration, and debridement. Infection associated with percutaneous VCD placement is uncommon, but it is an extremely serious complication. Early aggressive medical and surgical interventions are required to resolve this condition.