Abstract
We studied median, ulnar and peroneal motor nerve conduction velocity (NCV) and median sensory action potential (SAP) latency and amplitude in 18 insulin-dependent diabetic patients who were begun on a continuous subcutaneous insulin infusion (CSII) program. With institution of this therapy, significant decreases in mean blood glucose and glycosylated hemoglobin occurred. After 12 months of CSII treatment, median, peroneal, and ulnar motor NCVs all increased significantly. The average NCV increase was 2.5 m/s. Median SAP amplitude and latency did not significantly change. In a second group of 12 diabetic patients with the same mean age and comparable initial NCV and SAP measures, no significant changes in motor NCVs or SAPs occurred after 12 months of conventional insulin treatment. These results indicated the need for further long-term studies of the role of strict glucose control in the prevention of diabetic neuropathy.
Original language | English (US) |
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Pages (from-to) | 191-197 |
Number of pages | 7 |
Journal | Journal of the Neurological Sciences |
Volume | 74 |
Issue number | 2-3 |
DOIs | |
State | Published - Jul 1986 |
Keywords
- Diabetes
- Nerve conduction
- Neuropathy
ASJC Scopus subject areas
- Neurology
- Clinical Neurology