In Vivo Penetrating Microelectrodes for Brain Electrophysiology

Alexander Erofeev, Ivan Antifeev, Anastasia Bolshakova, Ilya Bezprozvanny, Olga Vlasova

Research output: Contribution to journalReview articlepeer-review


In recent decades, microelectrodes have been widely used in neuroscience to understand the mechanisms behind brain functions, as well as the relationship between neural activity and behavior, perception and cognition. However, the recording of neuronal activity over a long period of time is limited for various reasons. In this review, we briefly consider the types of penetrating chronic microelectrodes, as well as the conductive and insulating materials for microelectrode manufacturing. Additionally, we consider the effects of penetrating microelectrode implantation on brain tissue. In conclusion, we review recent advances in the field of in vivo microelectrodes.

Original languageEnglish (US)
Article number9085
Issue number23
StatePublished - Dec 2022
Externally publishedYes


  • brain
  • electrophysiology
  • in vivo
  • neural interface
  • neuronal activity

ASJC Scopus subject areas

  • Analytical Chemistry
  • Information Systems
  • Biochemistry
  • Atomic and Molecular Physics, and Optics
  • Instrumentation
  • Electrical and Electronic Engineering


Dive into the research topics of 'In Vivo Penetrating Microelectrodes for Brain Electrophysiology'. Together they form a unique fingerprint.

Cite this