Improvement of systemic lupus erythematosus activity by the association of delayed onset Cushing's syndrome

Kazuhiko Arima, Masanori Higuchi, Shigeru Yoshizawa, Takahiko Horiuchi, Kohei Nagasawa, Hitoshi Nakashima, Masatomo Taniguchi, Yoshiyuki Niho

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

We describe a 43-year-old woman with systemic lupus erythematosus (SLE) who had complete resolution of all SLE symptoms as a result of hypercortisolemia induced by a glucocorticoid-producing adenoma of the left adrenal gland. After an adrenalectomy, she developed an SLE exacerbation, characterized by photosensitivity, polyarthralgia, and hemolytic anemia, which required intensive steroid therapy. This is the first report of a patient with SLE entering apparent remission due to excessive adrenal secretion of glucocorticoids.

Original languageEnglish (US)
Pages (from-to)2456-2458
Number of pages3
JournalJournal of Rheumatology
Volume25
Issue number12
StatePublished - Dec 1998

Keywords

  • Cushing's syndrome
  • Glucocorticoid
  • Systemic lupus erythematosus

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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