Improved symptoms of complex regional pain syndrome after novel lymphatic treatment and interdisciplinary pain management

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Introduction: Complex regional pain syndrome (CRPS) is a pain syndrome with no singular mechanism and no specific cure. The aim of this case report is to study the impact of Lymphatic Enhancement Technology (LET) treatment on CRPS-related symptoms. Methods: A 51 year-old female presented with a chief complaint of severe, refractory ankle pain and CRPS related to a tibial and fibular fracture sustained three years earlier. The patient completed twelve cognitive behavioral therapy sessions over a 4-week period, and eleven physical therapy sessions over a four-month period, six of which utilized LET. Results: Pain and swelling were largely unchanged with interdisciplinary treatment before the introduction of LET. A within-session change of 37.5% in pain intensity and 87.5% in ankle girth was observed immediately after the first application of LET. Three months after beginning LET treatment, the patient maintained a 43.8% improvement in pain intensity and 100% improvement in measurements of lower extremity girth and ankle range of motion. No side effects or adverse events were associated with the LET treatment. Conclusion: Swelling, pain, and mobility loss are common symptoms and features of CRPS. LET is a novel, non-invasive treatment that appears to be quite safe and effective for improving pain, swelling, and mobility loss related to CRPS.

Original languageEnglish (US)
Article number101512
JournalComplementary Therapies in Clinical Practice
StatePublished - Feb 2022


  • Autonomic nervous system
  • Complex regional pain syndrome
  • Electrotherapy
  • Lymphatic system
  • Rehabilitation
  • Type i

ASJC Scopus subject areas

  • Complementary and alternative medicine


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