Image-guided thermal therapy

Rajiv Chopra

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations


Thermal therapy refers to the application of heat to treat disease. This therapeutic approach has been applied for over a century, with initial attempts involving the induction of fever to treat patients with advanced cancers. Since then, investigation into the biological basis for the therapeutic effect of heat, and the development of technology to deliver and monitor thermal therapies has improved the sophistication and accuracy of this treatment modality. The past decade has seen the rapid development of a diverse array of technology for heat generation as well as the introduction of novel noninvasive thermometric techniques such as magnetic resonance imaging (MRI). Today, quantitative knowledge of the temperature distribution within a heated volume, coupled with the ability to control the three-dimensional heating pattern makes thermal therapy a promising technique. These developments are generating a growing interest in the application of high temperatures (>60 ∞ C) capable of tissue thermal coagulation as a strategy for thermal therapy. The rapid and indiscriminate destruction of tissues exposed to these temperatures places high demands on the ability to monitor the deposition of energy and quantify the extent of thermal damage.

Original languageEnglish (US)
Title of host publicationBiomedical Technology and Devices Handbook
PublisherCRC Press
ISBN (Electronic)9781439870716
ISBN (Print)9780849311406
StatePublished - Jan 1 2003
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Engineering(all)
  • Materials Science(all)


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