Hyperviscosity syndrome attributable to hyperglobulinemia in chronic active hepatitis

William M. Lee, Oscar Lebwohl, Shu Chien

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

A young woman with clinical and histological features of chronic active hepatitis was noted to have extremely high levels of immunoglobulin (14.6 g per dl). This was associated with the hyperviscosity syndrome, diffuse coagulation abnormalities, and renal insufficiency in the absence of severe liver disease. Correction of these features occurred with plasmapheresis before corticosteroid therapy was begun. A similar group of persons with very high γ-globulin levels, described previously under the heading of "plasma cell hepatitis," may form a distinct and rare subgroup of chronic active hepatitis patients.

Original languageEnglish (US)
Pages (from-to)918-921
Number of pages4
JournalGastroenterology
Volume74
Issue number5 PART 1
DOIs
StatePublished - May 1978

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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