Hyperthyroidism and Hypothyroidism in Pregnancy

Brian M. Casey

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish (US)
Title of host publicationProtocols for High-Risk Pregnancies
Subtitle of host publicationAn Evidence-Based Approach
Number of pages6
ISBN (Print)9781405196505
StatePublished - Jul 9 2010


  • Clinical hypothyroidism complicating pregnancy - complications, gestational hypertension, placental abruption and preterm birth
  • Hyperthyroidism and hypothyroidism in pregnancy
  • Normal pregnancy, simulating clinical findings as in thyroxine (T4) excess
  • Overt hypothyroidism - complicating from 2 to 3 pregnancies per 1000
  • Pregnancy, substantial impact on maternal thyroid physiology
  • Symptomatic thyrotoxicosis or hyperthyroidism - complicating 1 in 1000 to 2000 pregnancies
  • Thyroid storm and heart failure - acute, life-threatening, hypermetabolic state, rare in pregnancy
  • Thyrotoxicosis during pregnancy - controlled by thionamide drugs
  • Transient leukopenia - in 10% of women taking antithyroid drugs
  • Women with thyrotoxicosis, pregnancy outcomes depended on metabolic control achieved

ASJC Scopus subject areas

  • Medicine(all)

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