@article{0db910cbe84b4f619fd3f7e41e0b70d5,
title = "Human immunodeficiency virus-associated atypical mycobacterial skeletal infections",
abstract = "The clinical and laboratory features of six human immunodeficiency virus (HIV)-positive patients with atypical mycobacterial skeletal infections, seen at a county outpatient HIV facility or university outpatient clinic, are reviewed and compared with other reported cases. Atypical mycobacterial skeletal infections are a manifestation of advanced HIV disease, with most cases having CD4 counts <100/mm3 at the time these infections become clinically apparent. Multiple sites are frequently involved, and concomitant skin infection with the same organism is common, especially with Mycobacterium haemophilum. The incidence of atypical mycobacterial skeletal infection in HIV-infected individuals was significantly higher than in the general county hospital district patient population, whereas the frequency of Myobacterium tuberculosis skeletal infection did not differ significantly between the two populations. The clinician therefore should maintain a high index of suspicion for atypical mycobacteria in a patient presenting with skeletal infection in the setting of a markedly depressed CD4 count.",
keywords = "Atypical mycobacteria, HIV-1 infection, osteomyelitis, septic arthritis",
author = "R. Hirsch and Miller, {S. M.} and S. Kazi and Cate, {T. R.} and Reveille, {J. D.}",
note = "Funding Information: From the Division of Rheumatology and Clinicall mmunoge-netics, Depamnent of Medicine, the University of Texas Health Science Center at Houston, and the Department of Medicine, Baylor College of Medicine, Houston, TX. Rosemarie Hirsch, MD, MPH: Fellow, Division of Rheumatology and Clinical Immunogenetics, Department of Medicine, the University of Texas Health Science Center at Houston, TX; Susan M. Miller, MD, MPH: Assistant Professor of Medicine, Department of Medicine, Baylor College of Medicine, Houston, TX; Salahuddin Kazi, MD: Fellow, Division of Rheuraatology and Clinical \[mmunogenetics, Department of Medicine, the University of Texas Health Science Center at Houston, TX; Thomas R. Cate, MD: Professor of Medicine, Department of Medicine, Baylor College of Medicine, Houston, TX; John D. Reveille, MD: Associate Professor of Medicine, Division of Rheumatology and ClinicalI mmunogenetics, Departmento fMedi-cine, the Universityo f Texas Health Science Centera t Houston, TX.. Supported in part by NIH grants R29-AR39345, ROI-AR42503, and MOI-RR-02558 (J.D.R.). Address reprint requests to John D. Reveille, MD, Division of Rheumatology, University of Texas Health Science Center-Houston, MSB 5.270, P.O. Box 20708, Houston, TX 77225. Copyright {\textcopyright} 1996 by W.B. Saunders Company 0049-0172 / 96/2505-000655. O0/0",
year = "1996",
doi = "10.1016/S0049-0172(96)80020-5",
language = "English (US)",
volume = "25",
pages = "347--356",
journal = "Seminars in Arthritis and Rheumatism",
issn = "0049-0172",
publisher = "W.B. Saunders Ltd",
number = "5",
}