HIV-1 Proviral Genome Engineering with CRISPR-Cas9 for Mechanistic Studies

Keyphrases

• Cas9 Protein 100%
• Cell Stimulation 33%
• Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) 33%
• Engineering Approach 33%
• Functional Cure 66%
• Genetic Engineering 100%
• Genomic Regulatory Elements 33%
• HIV Latency 33%
• HIV Transcription 33%
• HIV-1 Reactivation 33%
• Host Phases 33%
• Human Immunodeficiency Virus Type 1 (HIV-1) 100%
• Integration Site 33%
• Jurkat T Cells 33%
• Mechanistic Studies 100%
• Positive Feedback Loop 33%
• Provirus 33%
• Sequential Behavior 66%
• T Cell Clone 33%
• Therapeutic Approaches 33%
• Therapeutic Study 33%
• Transcription Factor 100%
• Transcriptional Profile 33%
• Transcriptional Program 33%
• Viral 100%
• Viral Genome 33%
• Viral Life Cycle 33%
• Viral Proteins 33%
• Viral Transcription 33%

Biochemistry, Genetics and Molecular Biology

• Cell Clone 20%
• Cell Stimulation 20%
• CRISPR 20%
• CRISPR/Cas9 100%
• Genome Editing 100%
• Human Immunodeficiency Virus 1 100%
• Life Cycle 20%
• Positive Feedback 20%
• Provirus 20%
• Regulatory Element 20%
• T Cell 20%
• Transcription 40%
• Transcription Factors 60%
• Viral Protein 20%

Immunology and Microbiology

• Cell Clone 20%
• Cell Stimulation 20%
• Clustered Regularly Interspaced Short Palindromic Repeat 20%
• CRISPR/Cas9 100%
• Genome Editing 100%
• Human Immunodeficiency Virus 1 100%
• Positive Feedback 20%
• Provirus 20%
• T Cell 20%
• Transcription Factors 60%
• Viral Life Cycle 20%
• Viral Protein 20%
• Viral Transcription 20%