High potency neuroleptics and violence in schizophrenics

John N. Herrera; John J. Sramek; Jerome F. Costa; Swati Roy; Chris W. Heh; Bich N. Nguyen

doi:10.1097/00005053-198809000-00009

High potency neuroleptics and violence in schizophrenics

John N. Herrera, John J. Sramek, Jerome F. Costa, Swati Roy, Chris W. Heh, Bich N. Nguyen

Psychiatry

Research output: Contribution to journal › Article › peer-review

56 Scopus citations

Abstract

In a controlled study, inpatient violence was measured during placebo, high-potency (haloperidol) and low-potency (chlorpromazine or clozapine) neuroleptics. Some patients had a marked increase in violent behavior with the moderately high-dose haloperidol, but not with low-potency neuroleptics. The authors discuss reasons for the increased violence with haloperidol, including akathisia and drug-induced behavioral toxicity.

Original language	English (US)
Pages (from-to)	558-561
Number of pages	4
Journal	Journal of Nervous and Mental Disease
Volume	176
Issue number	9
DOIs	https://doi.org/10.1097/00005053-198809000-00009
State	Published - Sep 1988

ASJC Scopus subject areas

Psychiatry and Mental health

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10.1097/00005053-198809000-00009

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AU - Nguyen, Bich N.

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High potency neuroleptics and violence in schizophrenics

Abstract

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