High NPM1-mutant allele burden at diagnosis predicts unfavorable outcomes in de novo AML

Sanjay S. Patel, Frank C. Kuo, Christopher J. Gibson, David P. Steensma, Robert J. Soiffer, Edwin P. Alyea, Yi Bin A. Chen, Amir T. Fathi, Timothy A. Graubert, Andrew M. Brunner, Martha Wadleigh, Richard M. Stone, Daniel J. DeAngelo, Valentina Nardi, Robert P. Hasserjian, Olga K. Weinberg