Heterotopic pregnancy

Mallory Stuparich, Kimberly A. Kho

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


The incidence of heterotopic pregnancy is estimated to be 1 in 30,000 pregnancies with the incidence rising to approximately 1 in 100 pregnancies with the use of assisted reproductive technologies. Detection of an intrauterine pregnancy does not rule out the possibility of a simultaneous ectopic pregnancy and vice versa. When a patient is diagnosed with a heterotopic pregnancy, prompt management is preferred to prevent the need for emergent treatment of a ruptured ectopic pregnancy. Systemic methotrexate should not be used to treat the ectopic portion of a heterotopic pregnancy due to the risks to the intrauterine pregnancy. The management of an unruptured ectopic pregnancy may be accomplished by local medical management (KCl or hyperosmolar glucose, but not methotrexate) or with surgery.

Original languageEnglish (US)
Title of host publicationEctopic Pregnancy: A Clinical Casebook
PublisherSpringer International Publishing
Number of pages7
ISBN (Print)9783319111407, 9783319111391
StatePublished - Jan 1 2015


  • Heterotopic pregnancy
  • Hyperosmolar glucose injection
  • KCl injection

ASJC Scopus subject areas

  • General Health Professions
  • General Medicine


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