Hemodynamic alterations during septal or right ventricular ischemia in dogs

David E Fixler, George A. Monroe, James M. Wheeler

Research output: Contribution to journalArticlepeer-review

42 Scopus citations


This study indicates that in dogs, ischemic injury to just the ventricular septum has little effect on left ventricular function. The data demonstrate that ischemic injury to either the right ventricular free wall or the ventricular septum alters right ventricular function and/or compliance, suggesting that both regions play a role in maintaining right ventricular performance. That septal contraction supports right ventricular function may explain why in earlier studies, right ventricular pressure development and output were little affected by severe injury to the free wall.

Original languageEnglish (US)
Pages (from-to)210-215
Number of pages6
JournalAmerican heart journal
Issue number2
StatePublished - Feb 1977

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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