Gynecomastia: A continuing diagnostic dilemma

J. D. Wilson

Research output: Contribution to journalEditorialpeer-review

4 Scopus citations


Breast enlargement in males can be a physiologic or idiopathic phenomenon occurring in newborns, adolescents, and possibly, normal elderly men; it can be the result of a feminizing state, or due to causes unknown.1 There are many causes of feminizing states, but most fall into three categories: absolute increases in estrogen formation as a result of direct secretion by tumors, increased availability of estrogen precursors, as in cirrhosis, or rare instances of hereditary increase in extraglandular synthesis of estrogen; relative increases in the ratio of estrogen to androgen, as in testicular failure; and drugs. The drugs are usually estrogens themselves,.

Original languageEnglish (US)
Pages (from-to)334-335
Number of pages2
JournalNew England Journal of Medicine
Issue number5
StatePublished - Jan 31 1991

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Gynecomastia: A continuing diagnostic dilemma'. Together they form a unique fingerprint.

Cite this