TY - JOUR
T1 - Guidelines for the prevention of intravascular catheter-related infections
AU - O'Grady, Naomi P.
AU - Alexander, Mary
AU - Dellinger, E. Patchen
AU - Gerberding, Julie L.
AU - Heard, Stephen O.
AU - Maki, Dennis G.
AU - Masur, Henry
AU - McCormick, Rita D.
AU - Mermel, Leonard A.
AU - Pearson, Michele L.
AU - Raad, Issam I.
AU - Randolph, Adrienne
AU - Weinstein, Robert A.
AU - Siegel, Jane D.
AU - Chinn, Raymond Y W
AU - DeMaria, Alfred
AU - Larson, Elaine L.
AU - Lee, James T.
AU - Moncada, Ramon E.
AU - Rutala, William A.
AU - Scheckler, William E.
AU - Stover, Beth H.
AU - Underwood, Marjorie A.
PY - 2002/12/1
Y1 - 2002/12/1
N2 - BACKGROUND: Although many catheter-related blood-stream infections (CRBSIs) are preventable, measures to reduce these infections are not uniformly implemented. OBJECTIVE: To update an existing evidenced-based guideline that promotes strategies to prevent CRBSIs. DATA SOURCES: The MEDLINE database, conference proceedings, and bibliographies of review articles and book chapters were searched for relevant articles. STUDIES INCLUDED: Laboratory-based studies, controlled clinical trials, prospective interventional trials, and epidemiologic investigations. OUTCOME MEASURES: Reduction in CRBSI, catheter colonization, or catheter-related infection. SYNTHESIS: The recommended preventive strategies with the strongest supportive evidence are education and training of healthcare providers who insert and maintain catheters; maximal sterile barrier precautions during central venous catheter insertion; use of a 2% chlorhexidine preparation for skin antisepsis; no routine replacement of central venous catheters for prevention of infection; and use of antiseptic/antibiotic-impregnated short-term central venous catheters if the rate of infection is high despite adherence to other strategies (ie, education and training, maximal sterile barrier precautions, and 2% chlorhexidine for skin antisepsis). CONCLUSION: Successful implementation of these evidence-based interventions can reduce the risk for serious catheter-related infection.
AB - BACKGROUND: Although many catheter-related blood-stream infections (CRBSIs) are preventable, measures to reduce these infections are not uniformly implemented. OBJECTIVE: To update an existing evidenced-based guideline that promotes strategies to prevent CRBSIs. DATA SOURCES: The MEDLINE database, conference proceedings, and bibliographies of review articles and book chapters were searched for relevant articles. STUDIES INCLUDED: Laboratory-based studies, controlled clinical trials, prospective interventional trials, and epidemiologic investigations. OUTCOME MEASURES: Reduction in CRBSI, catheter colonization, or catheter-related infection. SYNTHESIS: The recommended preventive strategies with the strongest supportive evidence are education and training of healthcare providers who insert and maintain catheters; maximal sterile barrier precautions during central venous catheter insertion; use of a 2% chlorhexidine preparation for skin antisepsis; no routine replacement of central venous catheters for prevention of infection; and use of antiseptic/antibiotic-impregnated short-term central venous catheters if the rate of infection is high despite adherence to other strategies (ie, education and training, maximal sterile barrier precautions, and 2% chlorhexidine for skin antisepsis). CONCLUSION: Successful implementation of these evidence-based interventions can reduce the risk for serious catheter-related infection.
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U2 - 10.1086/502007
DO - 10.1086/502007
M3 - Article
C2 - 12517020
AN - SCOPUS:0036916816
SN - 0899-823X
VL - 23
SP - 759
EP - 769
JO - Infection Control and Hospital Epidemiology
JF - Infection Control and Hospital Epidemiology
IS - 12
ER -