Abstract
Guanylin and uroguanylin are peptides that activate a membrane guanylate cyclase and control salt and water transport. Intestinal bacteria secrete toxins that mimic the actions of these peptides, causing a secretory form of diarrhea. Stimulation of guanylin/uroguanylin receptors in the kidney increases salt excretion. Thus guanylin and uroguanylin may regulate salt and water homeostasis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 17-24 |
| Number of pages | 8 |
| Journal | News in Physiological Sciences |
| Volume | 11 |
| Issue number | 1 |
| State | Published - Feb 1 1996 |
ASJC Scopus subject areas
- Physiology